abstract：:Circadian rhythms occur in hypothalamic serotonin content in the turkey. Inhibition of serotonin (5-HT) synthesis by parachlorophenylalanine (PCPA) blocks circadian variation in hypothalamic serotonin levels suggesting that the major cause of diurnal fluctuations is differing rates of synthesis of the amine. PCPA trea...

journal_title：Neuroendocrinology

authors： Martin JT,El Halawani M,Phillips RE

更新日期：1982-03-01 00:00:00

abstract：:Previous studies have shown that neonatal administration of monosodium glutamate (MSG) results in a clearly defined lesion of the arcuate nucleus which disrupts mechanisms regulating normal FSH but not LH secretion in the adult female hamster. The present study was designed to investigate the effects of neonatally adm...

journal_title：Neuroendocrinology

authors： Lamperti AA,Baldwin DM

更新日期：1982-03-01 00:00:00

abstract：:The distribution of gamma-aminobutyric acid (GABA) nerve fibers and cell bodies in the rat hypothalamus and pituitary gland was immunohistochemically examined using antibodies against the GABA-synthesizing enzyme glutamate decarboxylase (GAD). The dense network of GAD-positive nerve fibers was observed to be essential...

journal_title：Neuroendocrinology

authors： Vincent SR,Hökfelt T,Wu JY

更新日期：1982-02-01 00:00:00

abstract：:Diurnal variations, ranging over a twofold difference in concentrations of dopamine, norepinephrine and epinephrine, occur in the rat posterior pituitary gland during a 24-hour period. Highest catecholamine concentrations were seen during daylight hours and low levels reached a nadir 5 h after the onset of darkness. D...

journal_title：Neuroendocrinology

authors： Barden N,Chevillard C,Saavedra JM

更新日期：1982-02-01 00:00:00

abstract：:In the present study the effect of methadone (M) on gonadotropin-releasing hormone in the rat hypothalamus was investigated. The specificity of the M effect was demonstrated by injecting M (100 ng) and the M antagonist, naloxone (5 ng), into the ventromedial hypothalamus. A significant drop in the blood testosterone l...

journal_title：Neuroendocrinology

authors： Singh HH,Purohit V,Ahluwalia BS

更新日期：1982-01-01 00:00:00

abstract：:The influence of catecholamines (CA) on hypothalamic somatostatin (HPT-SRIF) was investigated in rats by using several drugs which interfere with brain CA metabolism. Depletion of brain CA stores by alpha-methyl-rho-tyrosine (AMT) increased HPT-SRIF, while augmented brain CA levels following L-dopa administration decr...

journal_title：Neuroendocrinology

authors： Torres I,Guaza C,Fernandez-Durango R,Borrell J,Charro AL

更新日期：1982-01-01 00:00:00

abstract：:Substance P (SP) is known to act on pituitary hormone release either at the hypothalamic level or directly at the pituitary level. In order to investigate whether SP is present in the pituitary gland and to localize the peptide at the cellular and subcellular levels, the immunocytological method was used. Rat pituitar...

journal_title：Neuroendocrinology

authors： Morel G,Chayvialle JA,Kerdelhue B,Dubois PM

更新日期：1982-01-01 00:00:00

abstract：:Prolactin-releasing (PRF) activity was found in Pitressin (a commercial extract from posterior pituitary for vasopressin). Injection of Pitressin into conscious free-moving rats implanted with a permanent atrial indwelling cannula, produced a transient increase in prolactin concentration in the circulation. In order t...

journal_title：Neuroendocrinology

authors： Shin SH

更新日期：1982-01-01 00:00:00

abstract：:The effects of melatonin administration on thyroid physiology of female hamsters was investigated. A protocol of 25 micrograms given daily as subcutaneous injections late in the light period was found to inhibit blood levels of thyroxin (T4), triiodothyronine (T3) and thyrotropin (TSH). The free T4 index (FT4I) and th...

journal_title：Neuroendocrinology

authors： Vriend J,Richardson BA,Vaughan MK,Johnson LY,Reiter RJ

更新日期：1982-01-01 00:00:00

abstract：:The effect of sonicated suspensions of phosphatidylserine (PS), an acidic phospholipid, was investigated on prolactin secretion utilizing in vivo and in vitro approaches. Acute and chronic administration of PS reduced plasma prolactin levels during different phases of circadian rhythms. The phospholipid was able to in...

journal_title：Neuroendocrinology

authors： Canonico PL,Annunziato L,Toffano G,Bernardini R,Stanzani S,Foti M,Clementi G,Drago F,Scapagnini U

更新日期：1981-12-01 00:00:00

abstract：:In order to characterize plasma prolactin (Prl) patterns during the estrous cycle and pseudopregnancy (PSP), I collected sequential blood samples between 8.00 and 19.00 h at 1-hour, 1.5-min or 1-min intervals from conscious, unrestrained female rats. During the afternoon of proestrus and estrus a single Prl surge was ...

journal_title：Neuroendocrinology

authors： Wiersma J

更新日期：1981-11-01 00:00:00

abstract：:Single rat neurohypophyses were impaled on a platinum electrode, perifused with isotonic medium and fractions of perifusate collected each minute. Arginine vasopressin content of the fractions was measured by radioimmunoassay. The basal release of arginine vasopressin varied from 50 to 350 pg (0.02-0.14 mU/min) betwee...

journal_title：Neuroendocrinology

authors： Bicknell RJ,Leng G

更新日期：1981-11-01 00:00:00

abstract：:We have investigated the effects of exposure to short-term constant light (LL) on the spontaneous, proestrous luteinizing hormone (LH) surge in the female rat. Exposure to LL during the 3 days preceding proestrus delayed and reduced the magnitude of the LH surge which was measured in blood samples taken from conscious...

journal_title：Neuroendocrinology

authors： Watts AG,Fink G

更新日期：1981-09-01 00:00:00

abstract：:The effects of linear (L) or cyclic (C) somatostatin (SRIF) on the release of growth hormone (GH) as measured both by bioassay and by radioimmunoassay (RIA) were studied in a series of incubation experiments with rat adenohypophyses. Although both forms of SRIF inhibited release of RIA-GH in all experiments, only C-SR...

journal_title：Neuroendocrinology

authors： Russell SM

更新日期：1981-08-01 00:00:00

abstract：:Rats bearing transplanted prolactin-secreting tumors are known to have very high prolactin levels in the serum, reduced hypothalamic opiate concentrations, increasing hypothalamic dopamine synthesis and increased hypophyseal portal blood dopamine levels. Further, it has been shown that incubation in 3H-leucine of ante...

journal_title：Neuroendocrinology

authors： Login IS,Nagy I,MacLeod RM

更新日期：1981-08-01 00:00:00

abstract：:Phase relation between plasma corticosterone and locomotor activity rhythms was analyzed in individual rats with selective lesions of suprachiasmatic nuclei (SCN). SCN in Wistar male rats were selectively coagulated electrically and the extent of SCN destruction was examined histologically. Spontaneous locomotor activ...

journal_title：Neuroendocrinology

authors： Watanabe K,Hiroshige T

更新日期：1981-07-01 00:00:00

abstract：:The timing of the episodic secretion of luteinizing hormone (LH) in ovariectomized ewes was investigated with respect to an ultradian rest-activity cycle. Individual sheep were enclosed in a chamber where their physical activity was continuously monitored, and blood samples for LH analysis were collected at 5-min inte...

journal_title：Neuroendocrinology

authors： Rasmussen DD,Malven PV

更新日期：1981-06-01 00:00:00

abstract：:The ability of dopamine receptor antagonists to stimulate prolactin release in rats with medial basal hypothalamic lesions was investigated. Starting levels of prolactin were elevated to approximately 400 ng/ml in animals in which the tuberoinfundibular dopaminergic neurons were completely destroyed by the lesion. In ...

journal_title：Neuroendocrinology

authors： Cheung CY,Neill AC,Weiner RI

更新日期：1981-06-01 00:00:00

abstract：:Hypothalamic norepinephrine (NE) and dopamine content was studied in dogs with spontaneous and iatrogenic hypercortisolism and in untreated normal dogs. The concentration of NE in the hypothalamus was subnormal in 4 of 8 dogs with pituitary-dependent hyperadrenocorticism (PDH), whereas long-term administration of cort...

journal_title：Neuroendocrinology

authors： Meijer JC,Croughs RJ,Rijnberk A,Versteeg DH,van Ree JM

更新日期：1981-04-01 00:00:00

abstract：:Hypophysectomized male rats with adenohypophyses grafted under the kidney capsule (HG rat) for 3 weeks with or without estradiol implantation, were used to examine prolactin (PRL) secretion independent of hypothalamic influence. Changes in the circulating PRL concentration were monitored by taking blood samples every ...

journal_title：Neuroendocrinology

authors： Shin SH,Reifel CW

更新日期：1981-03-01 00:00:00

abstract：:These studies investigated the effect of aging on thyroid hormone regulation of beta-endorphin in rat corpus striatum and hypothalamus. In both brain areas, basal levels of beta-endorphin declined with age. In addition, age modified the response of beta-endorphin to thyroid hormone status. Hypothyroid rats aged 6 mont...

journal_title：Neuroendocrinology

authors： Gambert SR

更新日期：1981-02-01 00:00:00

abstract：:The effects of (D-Met2,Pro5)-enkephalinamide--a superactive enkephalin analogue--on the preovulatory discharge of gonadotrophic hormones and on ovulation were investigated. Injection of the opioid (16 nmol) into a lateral cerebral ventricle of regularly cycling female rats immediately before the critical period on the...

journal_title：Neuroendocrinology

authors： Köves K,Marton J,Molnár J,Halász B

更新日期：1981-02-01 00:00:00

abstract：:An electrophysiological investigation was conducted on the connection of medial preoptic neurons with the median eminence and the basal and corticomedial amygdala in pentobarbital anesthesized male Sprague-Dawley rats. Of 411 medial preoptic neurons tested with median eminence stimuli, antidromic responses (mean laten...

journal_title：Neuroendocrinology

authors： Layton BS,Lafontaine S,Renaud LP

更新日期：1981-01-01 00:00:00

abstract：:The pressor effect of intravenous angiotensin II (AII) was compared in the unrestrained rat before and after electrolytic lesions of the subfornical organ (SFO), the circumventricular organ of the dorsal third cerebral ventricle. Abdominal aortic and venal caval catheters were used to measure arterial pressure and to ...

journal_title：Neuroendocrinology

authors： Mangiapane ML,Simpson JB

更新日期：1980-12-01 00:00:00

abstract：:The effect of castration and adrenalectomy was studied on vasoactive intestinal peptide (VIP) concentrations in various brain and peripheral structures of male rats. Castration has no effect on any of the structures studied, whereas 4 weeks adrenalectomy (ADX) decreases VIP concentrations in the hippocampus and increa...

journal_title：Neuroendocrinology

authors： Rotsztejn WH,Besson J,Briaud B,Gagnant L,Rosselin G,Kordon C

更新日期：1980-10-01 00:00:00

abstract：:The differences in plasma prolactin concentration between normal and estradiol-implanted male rats were compared after treatment with 3 different stimulating agents of prolactin secretion [ether anesthesia, pimozide (a "specific' dopaminergic receptor blocking agent) and TRH] using conscious, free-moving rats implante...

journal_title：Neuroendocrinology

authors： Piercy M,Shin SH

更新日期：1980-10-01 00:00:00

abstract：:VIP stimulated prolactin secretion from incubated rat hemipituitaries. Under the same conditions, the secretion of GH, LH, FSH was not affected. The stimulation of prolactin was dose-dependent, with an apparent affinity of VIP of 10.9 +/- 3.1 nM and a maximal stimulation of 57.7 +/- 4.2%. Secretin, a structurally rela...

journal_title：Neuroendocrinology

authors： Enjalbert A,Arancibia S,Ruberg M,Priam M,Bluet-Pajot MT,Rotsztejn WH,Kordon C

更新日期：1980-09-01 00:00:00

abstract：:The present study was undertaken to evaluate the 24-hour periodicity in serum prolactin levels subsequent to transecting the ascending serotonergic system or ablating the suprachiasmatic nuclei (SCN) of adult (185 g) female rats. The ascending serotonergic system was transected at the level of the rostral mesencephalo...

journal_title：Neuroendocrinology

authors： Dunn JD,Johnson DC,Castro AJ,Swenson R

更新日期：1980-08-01 00:00:00

abstract：:We measured the concentration of oxytocin and vasopressin in microdissected areas of the hypothalamus and posterior pituitary in weanling and adult female rats. Oxytocin concentration was significantly less in adult rats as compared to weanling rats in the supraoptic nucleus, median eminence, and retrochiasmatic area ...

journal_title：Neuroendocrinology

authors： Jackson R,George JM

更新日期：1980-08-01 00:00:00

abstract：:Administration of the bovine pineal peptide threonylseryllysine (TSL) to unilaterally ovariectomized (UO) mice as a single intraperitoneal injection on the day of UO reduced the 5-day compensatory ovarian hypertrophy. The same dose of TSL (175 ng/animal) significantly (p less than 0.01) reduced serum follicle stimulat...

journal_title：Neuroendocrinology

authors： Orts RJ,Bruot BC,Sartin JL

更新日期：1980-08-01 00:00:00

abstract：:(+/-)p-Chloroamphetamine hydrochloride, at doses of 1-8 mg/kg i.p. in rats, caused a dose-related increase in serum corticosterone concentration. The increase occurred rapidly, within 30 min, and was over within 4 h. Evidence that the increase was mediated by serotonin release consisted of the following findings: (1) ...

journal_title：Neuroendocrinology

authors： Fuller RW,Snoddy HD

更新日期：1980-08-01 00:00:00

abstract：:In the Siberian hamster the pituitary content of bioassayable MSH has been shown to be seasonally variable, being greater during the long days of spring and summer than during the short days of autumn and winter. Similar changes in the pituitary content of both bioassayable MSH and immunoreactive alpha MSH can be indu...

journal_title：Neuroendocrinology

authors： Logan A,Weatherhead B

更新日期：1980-05-01 00:00:00

abstract：:The purpose of this study was to determine the effect of rendering newborn male Sprague-Dawley rats hypothyroid with 131I on development of the hypothalamic-pituitary axis. Hormonal responses to thyrotropin-releasing hormone (TRH), haloperidol (H), and luteinizing hormone-releasing hormone (LHRH) were determined at 9,...

journal_title：Neuroendocrinology

authors： Sowers JR,Resch G,Walker S,Sollars E

更新日期：1980-05-01 00:00:00

abstract：:Using two tests in intact adult rats, it has been found that a high positive correlation exists (p less than 0.005) between the ovulation inhibiting and the serotonin antagonistic activities measured in vivo of five tricyclic compounds and ten ergot derivatives. In these chemically different classes of compounds, cert...

journal_title：Neuroendocrinology

authors： Markó M,Flückiger E

更新日期：1980-04-01 00:00:00

abstract：:The feedback effect of systemically administered dexamethasone on basal plasma corticosterone levels and on adrenocortical responses to ether plus skin incision stress were studied in intact rats and in animals with bilateral dorsal or ventral hippocampectomy or fimbria section. It was found that in rats with ventral ...

journal_title：Neuroendocrinology

authors： Feldman S,Conforti N

更新日期：1980-01-01 00:00:00

abstract：:The possible role of prostaglandins (PGs) in the hypothalamic control of ovulation has been investigated by studying the effects of indomethacin (ID) and PGs on the release of luteinizing hormone-releasing hormone (LHRH) from hypothalamic synaptosomes. Female rats were chronically pretreated with ID on diestrus 2 (D2)...

journal_title：Neuroendocrinology

authors： Linton EA,Bennett GW,Whitehead SA

更新日期：1979-01-01 00:00:00

abstract：:Anterior pituitaries from female Sprague-Dawley rats (160-200 g b.w) bearing electrolytic lesions of the median eminence were qualitatively and quantitatively investigated by electron microscopy and the findings compared with those from intact animals or sham-operated controls. This study was performed in basal condit...

journal_title：Neuroendocrinology

authors： Rossi GL,Probst D,Panerai AE,Cocchi D,Locatelli V,Müller EE

更新日期：1979-01-01 00:00:00

abstract：:Acute electrolytic stimulation of the median raphe (MR) nucleus (MR Stim) between 13:00 and 16:00 h on proestrus blocked ovulation in 10 of the 21 rats tested, whereas all sham-treated (MR Sham, no current) animals ovulated normally (n = 12). MR Stim at 16:00 h on proestrus in individual cannulated rats 'turned off' t...

journal_title：Neuroendocrinology

authors： Barofsky AL

更新日期：1979-01-01 00:00:00

abstract：:Serum Glucose concentrations were measured before and after electrical stimulation in the ventromedial and supramamillary nuclei of the hypothalamus. 27 fed rats of both sexes were anesthetized with Sodium Pentobarbital. A 36 gauge nichrome electrode was positioned stereotaxically within the rat brain. Stimulus parame...

journal_title：Neuroendocrinology

authors： Gisel EG,Innes DL

更新日期：1979-01-01 00:00:00

abstract：:An abolishment of 24 h periodicity of the adrenocortical activity was observed in rats subjected to a prolonged food deprivation of 7--8 days. Total locomotor activity progressively decreased and its circadian rhythm faded out in a similar fashion as the adrenocortical rhythm. The circadian rhythms of both locomotor a...

journal_title：Neuroendocrinology

authors： Kobayashi K,Takahashi K

更新日期：1979-01-01 00:00:00